Thermo HM 355S Microtome

The Thermo Scientific™ Microm HM 355S is a high-performance automated rotary microtome designed to deliver precise, consistent sectioning for routine histology, pathology, and research laboratories. Engineered for both paraffin and hard tissue applications, the HM 355S combines advanced automation, ergonomic operation, and enhanced safety features to improve workflow efficiency while reducing operator fatigue.

Its electronically controlled motorized cutting system provides smooth, reproducible sectioning with adjustable section thickness ranging from 0.5 to 100 μm and trimming thickness from 5 to 500 μm. Multiple operating modes — including single, interval, multi, and continuous sectioning — allow laboratories to customize performance based on specimen requirements and workflow demands.

The HM 355S features an intuitive menu-driven control panel that can be positioned on either side of the instrument for improved operator comfort and accessibility. Additional conveniences such as joystick specimen advance and rewind controls, selectable trimming and sectioning speeds, rocking mode trimming, and optional foot pedal operation help streamline daily sectioning procedures while maximizing productivity.

Designed with operator safety and specimen protection in mind, the HM 355S incorporates an emergency stop system, automatic motor brake functionality, handwheel locking mechanisms, and blade safety features to enhance safe operation during sectioning and blade handling. Its durable construction, guide-rail guidance system, and precision specimen orientation controls help ensure accurate, repeatable section quality across a wide range of laboratory applications.